Integrative proteogenomic analyses of human tumours identifies ADNP as a novel oncogenic mediator of cell cycle progression in high-grade serous ovarian cancer with poor prognosis

BACKGROUND: Despite toxic side effects and limited durable response, the current standard-of-care treatment for high grade serous ovarian cancer (HGSOC) remains platinum/taxane-based chemotherapy. Given that the overall prognosis has not improved drastically over the past several decades, there is a...

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Vydáno v:EBioMedicine
Hlavní autoři: Karagoz, Kubra, Mehta, Gaurav A., Khella, Christen A., Khanna, Pooja, Gatza, Michael L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921307/
https://ncbi.nlm.nih.gov/pubmed/31767542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.009
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