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Preparation, Characterization, and In Vivo Pharmacokinetic Study of the Supercritical Fluid-Processed Liposomal Amphotericin B

Here, we aimed to prepare and optimize liposomal amphotericin B (AmB) while using the supercritical fluid of carbon dioxide (SCF-CO(2)) method and investigate the characteristics and pharmacokinetics of the SCF-CO(2)-processed liposomal AmB. Liposomes containing phospholipids, ascorbic acid (vit C),...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Lim, Chang-baek, Abuzar, Sharif Md, Karn, Pankaj Ranjan, Cho, Wonkyung, Park, Hee Jun, Cho, Cheong-Weon, Hwang, Sung-Joo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921013/
https://ncbi.nlm.nih.gov/pubmed/31717352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110589
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