Antibody-Based Targeting of Cell Surface GRP94 Specifically Inhibits Cetuximab-Resistant Colorectal Cancer Growth

Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. Cetuximab, a human/mouse chimeric monoclonal antibody, is effective in a limited number of CRC patients because of cetuximab resistance. This study aimed to identify novel therapeutic targets in cetuximab-resistant CRC i...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Jeoung, Mee Hyun, Kim, Taek-Keun, Kim, Ji Woong, Cho, Yea Bin, Na, Hee Jun, Yoo, Byong Chul, Shim, Hyunbo, Song, Dong-Keun, Heo, Kyun, Lee, Sukmook
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920916/
https://ncbi.nlm.nih.gov/pubmed/31683810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110681
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