Development of Folate-Functionalized PEGylated Zein Nanoparticles for Ligand-Directed Delivery of Paclitaxel

In this study, we investigated the active targeted delivery of a hydrophobic drug, paclitaxel (PTX), via receptor-mediated endocytosis by folate receptors expressed on cancer cells using a protein-based nanoparticle system. PTX was loaded on zein nanoparticles and conjugated with folate (PTX/Zein-FA...

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Gepubliceerd in:Pharmaceutics
Hoofdauteurs: Soe, Zar Chi, Ou, Wenquan, Gautam, Milan, Poudel, Kishwor, Kim, Bo Kyun, Pham, Le Minh, Phung, Cao Dai, Jeong, Jee-Heon, Jin, Sung Giu, Choi, Han-Gon, Ku, Sae Kwang, Yong, Chul Soon, Kim, Jong Oh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920870/
https://ncbi.nlm.nih.gov/pubmed/31671569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110562
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