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Molecular Dynamics Simulations Suggest a Non-Doublet Decoding Model of −1 Frameshifting by tRNA(Ser3)

In-frame decoding in the ribosome occurs through canonical or wobble Watson–Crick pairing of three mRNA codon bases (a triplet) with a triplet of anticodon bases in tRNA. Departures from the triplet–triplet interaction can result in frameshifting, meaning downstream mRNA codons are then read in a di...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Caulfield, Thomas, Coban, Matt, Tek, Alex, Flores, Samuel Coulbourn
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920855/
https://ncbi.nlm.nih.gov/pubmed/31752208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110745
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