Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As a Novel Inhibitor of HMGA2 in Colorectal Cancer

Human high-mobility group A2 (HMGA2) encodes for a non-histone chromatin protein which influences a variety of biological processes, including the cell cycle process, apoptosis, the DNA damage repair process, and epithelial–mesenchymal transition. The accumulated evidence suggests that high expressi...

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Huang, Yu-Min, Cheng, Chia-Hsiung, Pan, Shiow-Lin, Yang, Pei-Ming, Lin, Ding-Yen, Lee, Kuen-Haur
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920845/
https://ncbi.nlm.nih.gov/pubmed/31684108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110688
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