C(60) Fullerene as an Effective Nanoplatform of Alkaloid Berberine Delivery into Leukemic Cells

A herbal alkaloid Berberine (Ber), used for centuries in Ayurvedic, Chinese, Middle-Eastern, and native American folk medicines, is nowadays proved to function as a safe anticancer agent. Yet, its poor water solubility, stability, and bioavailability hinder clinical application. In this study, we ha...

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Veröffentlicht in:Pharmaceutics
Hauptverfasser: Grebinyk, Anna, Prylutska, Svitlana, Buchelnikov, Anatoliy, Tverdokhleb, Nina, Grebinyk, Sergii, Evstigneev, Maxim, Matyshevska, Olga, Cherepanov, Vsevolod, Prylutskyy, Yuriy, Yashchuk, Valeriy, Naumovets, Anton, Ritter, Uwe, Dandekar, Thomas, Frohme, Marcus
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920783/
https://ncbi.nlm.nih.gov/pubmed/31717305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11110586
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