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An increase of excitatory-to-inhibitory synaptic balance in the contralateral cortico-striatal pathway underlies improved stroke recovery in BDNF Val66Met SNP mice

Despite negative association in cognition and memory, mice harboring Val66Met BDNF SNP (BDNF(M/M)) exhibit enhanced motor recovery accompanied by elevated excitatory synaptic markers VGLUT1 and VGLUT2 in striatum contralateral to unilateral ischemic stroke. The cortico-striatal pathway is a critical...

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Detalhes bibliográficos
Publicado no:Neurorehabil Neural Repair
Main Authors: Qin, Luye, Actor-Engel, Hanna S., Woo, Moon-Sook, Shakil, Faariah, Chen, Yi-Wen, Cho, Sunghee, Aoki, Chiye
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920539/
https://ncbi.nlm.nih.gov/pubmed/31524060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1545968319872997
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