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CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance
The use of taxanes has for decades been crucial for treatment of several cancers. A major limitation of these therapies is inherent or acquired drug resistance. A key to improved outcome of taxane-based therapies is to develop tools to predict and monitor drug efficacy and resistance in the clinical...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920357/ https://ncbi.nlm.nih.gov/pubmed/31852908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55526-8 |
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