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A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells

Understanding the mechanisms involved in HIV infection and latency, and development of a cure, rely on the availability of sensitive research tools such as indicator cells, which allow rigorous quantification of viral activity. Here we describe the construction and validation of a novel dual-indicat...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Salasc, Fanny, Gludish, David W., Jarvis, Isobel, Boliar, Saikat, Wills, Mark R., Russell, David G., Lever, Andrew M. L., Mok, Hoi-Ping
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920355/
https://ncbi.nlm.nih.gov/pubmed/31852924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55596-8
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