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Development of a Novel DNA Oligonucleotide Targeting Low-Density Lipoprotein Receptor

Low-density lipoprotein receptor (LDL-R) is a cell surface receptor protein expressed in a variety of solid cancers, including lung, colon, breast, brain, and liver, and therefore it opens up opportunities to deliver lysosome-sensitive anti-cancer agents, especially synthetic nucleic acid-based ther...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Wang, Tao, Rahimizadeh, Kamal, Veedu, Rakesh N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920325/
https://ncbi.nlm.nih.gov/pubmed/31841991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.11.004
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