AAV-miR-204 Protects from Retinal Degeneration by Attenuation of Microglia Activation and Photoreceptor Cell Death

Inherited retinal diseases (IRDs) represent a frequent cause of genetic blindness. Their high genetic heterogeneity hinders the application of gene-specific therapies to the vast majority of patients. We recently demonstrated that the microRNA miR-204 is essential for retinal function, although the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Karali, Marianthi, Guadagnino, Irene, Marrocco, Elena, De Cegli, Rossella, Carissimo, Annamaria, Pizzo, Mariateresa, Casarosa, Simona, Conte, Ivan, Surace, Enrico Maria, Banfi, Sandro
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920266/
https://ncbi.nlm.nih.gov/pubmed/31837604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.11.005
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