Angiotensin II Type I Receptor Antagonism Attenuates Nicotine-Induced Cardiac Remodeling, Dysfunction, and Aggravation of Myocardial Ischemia-Reperfusion Injury in Rats

Increased exposure to nicotine contributes to the development of cardiac dysfunction by promoting oxidative stress, fibrosis, and inflammation. These deleterious events altogether render cardiac myocytes more susceptible to acute cardiac insults such as ischemia-reperfusion (I/R) injury. This study...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ramalingam, Anand, Budin, Siti Balkis, Mohd. Fauzi, Norsyahida, Ritchie, Rebecca H., Zainalabidin, Satirah
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920178/
https://ncbi.nlm.nih.gov/pubmed/31920673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01493
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