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Structure and function of the insulin receptor—a personal perspective

Immunoprecipitation with autoantibodies to the insulin receptor derived from patients with extreme insulin resistance and acanthosis nigricans revealed that the receptor is comprised of two subunits of 135 kDa (α subunit) and 95 kDa (β subunit) and that insulin induces the rapid phosphorylation of t...

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Bibliographic Details
Published in:Proc Jpn Acad Ser B Phys Biol Sci
Main Author: KASUGA, Masato
Format: Artigo
Language:Inglês
Published: The Japan Academy 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920081/
https://ncbi.nlm.nih.gov/pubmed/31827016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.95.039
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