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Blocker escape kinetics from a membrane channel analyzed by mapping blocker diffusive dynamics onto a two-site model

When a large solute molecule enters a membrane channel from the membrane-bathing electrolyte solution, it blocks the small-ion current flowing through the channel. If the molecule spends in the channel sufficiently long time, individual blockades can be resolved in single-channel experiments. In thi...

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Detalles Bibliográficos
Publicado en:J Chem Phys
Main Authors: Berezhkovskii, Alexander M., Bezrukov, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado: AIP Publishing LLC 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920014/
https://ncbi.nlm.nih.gov/pubmed/31117787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5095594
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