Catalase Functionalized Iron Oxide Nanoparticles Reverse Hypoxia Induced Chemotherapeutic Resistance

Intratumoral hypoxia is a major contributor to multiple drug resistance (MDR) in cancer, and can lead to poor prognosis of patients receiving chemotherapy. Development of an MDR-inhibitor that mitigates the hypoxic environment is crucial for cancer management and treatment. We report a biocompatible...

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Bibliografiske detaljer
Udgivet i:Adv Healthc Mater
Main Authors: Yen, Tin-Yo, Stephen, Zachary R., Lin, Guanyou, Mu, Qingxin, Jeon, Mike, Untoro, Stela, Welsh, Parker, Zhang, Miqin
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919328/
https://ncbi.nlm.nih.gov/pubmed/31557421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201900826
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