Dominant and Sensitive Control of Oxidative Flux by the ATP-ADP Carrier in Human Skeletal Muscle Mitochondria: Effect of Lysine Acetylation

The adenine nucleotide translocase (ANT) of the mitochondrial inner membrane exchanges ADP for ATP. Mitochondria were isolated from human vastus lateralis muscle (n=9). Carboxyatractyloside titration of O(2) consumption rate (J(o)) at clamped [ADP] of 21 μM gave ANT abundance of 0.97 ± 0.14 nmol ANT...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Willis, WT, Miranda-Grandjean, D, Hudgens, J, Willis, EA, Finlayson, J, De Filippis, EA, Bustos, R Zapata, Langlais, PR, Mielke, C, Mandarino, LJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919326/
https://ncbi.nlm.nih.gov/pubmed/29653079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.04.006
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