A Type IV-A CRISPR-Cas System in Pseudomonas aeruginosa Mediates RNA-Guided Plasmid Interference In Vivo

Bacteria and archaea use CRISPR-Cas adaptive immune systems to destroy complementary nucleic acids using RNAs derived from CRISPR loci. Here, we provide the first functional evidence for type IV CRISPR-Cas, demonstrating that the system from Pseudomonas aeruginosa strain PA83 mediates RNA-guided int...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:CRISPR J
Glavni autori: Crowley, Valerie M., Catching, Adam, Taylor, Hannah N., Borges, Adair L., Metcalf, Josie, Bondy-Denomy, Joseph, Jackson, Ryan N.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc., publishers 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919247/
https://ncbi.nlm.nih.gov/pubmed/31809194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/crispr.2019.0048
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items