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Preliminary Capillary Flow Experiments with Amyloid-β, Possible Needle and Capillary Aβ Adsorption, and a Proposal for Drug Evaluation Under Shear Conditions

 Amyloid-β (Aβ) solution injections into an aqueous mobile phase moving through narrow bore stainless-steel capillary tubing results in adsorption of at least 99% Aβ within the tubing or injection valve. However, if flow is stopped for a period of 5–10 minutes, then started, wall desorption yields A...

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Publicat a:J Alzheimers Dis
Autors principals: Trumbore, Conrad N., Paik, Jennie, Fay, David, Vachet, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918921/
https://ncbi.nlm.nih.gov/pubmed/31640094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190522
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