Calcilytic NPS 2143 Reduces Amyloid Secretion and Increases sAβPPα Release from PSEN1 Mutant iPSC-Derived Neurons

Despite numerous efforts and studies over the last three decades, Alzheimer’s disease (AD) remains a disorder not fully understood and incurable so far. Development of induced pluripotent stem cell (iPSC) technology to obtain terminally differentiated neurons from adult somatic cells revolutionized...

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Bibliographic Details
Published in:J Alzheimers Dis
Main Authors: Lo Giudice, Maria, Mihalik, Balázs, Turi, Zsófia, Dinnyés, András, Kobolák, Julianna
Format: Artigo
Language:Inglês
Published: IOS Press 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918902/
https://ncbi.nlm.nih.gov/pubmed/31640098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190602
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