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UV-dependent phosphorylation of COP9/signalosome in UV-induced apoptosis

The COP9/signalosome (CSN) multi-protein complex regulates the activity of cullin-RING ubiquitin ligases (CRLs), including the DDB2 and CSA CRL4 ligases (CRL4(DDB2) and CRL4(CSA)), which are involved in the repair of UV-induced DNA damages. In the present study, we demonstrated that the protein kina...

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Bibliografiske detaljer
Udgivet i:Oncol Rep
Main Authors: Dubois, Emilie Laure, Gerber, Scott, Kisselev, Alexei, Harel-Bellan, Annick, Groisman, Regina
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918815/
https://ncbi.nlm.nih.gov/pubmed/26986008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4671
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