Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy

Notch pathway activation plays a central role in the pathogenesis of many glomerular diseases. We have previously shown that Notch4 expression was upregulated in various renal cells in human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) patients and rodent models of HIVAN. In this stud...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Puri, Rajni Vaid, Yerrathota, Sireesha, Home, Trisha, Idowu, Jessica Y., Chakravarthi, V. Praveen, Ward, Christopher J., Singhal, Pravin C., Vanden Heuvel, Gregory B., Fields, Timothy A., Sharma, Madhulika
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918754/
https://ncbi.nlm.nih.gov/pubmed/31727625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.040642
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