Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem

BACKGROUND: Dry eye disease (DED) is a multifactorial disease associated with ocular surface inflammation, pain, and nerve abnormalities. We studied the peripheral and central neuroinflammatory responses that occur during persistent DED using molecular, cellular, behavioral, and electrophysiological...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Fakih, Darine, Zhao, Zhanlin, Nicolle, Pierre, Reboussin, Elodie, Joubert, Fanny, Luzu, Jade, Labbé, Antoine, Rostène, William, Baudouin, Christophe, Mélik Parsadaniantz, Stéphane, Réaux-Le Goazigo, Annabelle
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918709/
https://ncbi.nlm.nih.gov/pubmed/31847868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1656-4
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