PARP-1 deregulation in multiple sclerosis

BACKGROUND: Poly (ADP-ribose) polymerase 1 (PARP-1) plays pivotal roles in immune and inflammatory responses. Accumulating evidence suggests PARP-1 as a promising target for immunomodulation in multiple sclerosis and natalizumab-associated progressive multifocal leukoencephalopathy. OBJECTIVE: This...

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Bibliografske podrobnosti
izdano v:Mult Scler J Exp Transl Clin
Main Authors: Meira, Maria, Sievers, Claudia, Hoffmann, Francine, Bodmer, Heidi, Derfuss, Tobias, Kuhle, Jens, Haghikia, Aiden, Kappos, Ludwig, Lindberg, Raija LP
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2019
Teme:
Original Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918498/
https://ncbi.nlm.nih.gov/pubmed/31897308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2055217319894604
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