Multi-Organ NMR Metabolomics to Assess In Vivo Overall Metabolic Impact of Cisplatin in Mice

This work describes, to our knowledge, the first NMR metabolomics analysis of mice kidney, liver, and breast tissue in response to cisplatin exposure, in search of early metabolic signatures of cisplatin biotoxicity. Balb/c mice were exposed to a single 3.5 mg/kg dose of cisplatin and then euthanize...

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Bibliographic Details
Published in:Metabolites
Main Authors: Carneiro, Tatiana J., Araújo, Rita, Vojtek, Martin, Gonçalves-Monteiro, Salomé, Diniz, Carmen, Batista de Carvalho, Ana L.M., Marques, Maria Paula M., Gil, Ana M.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918135/
https://ncbi.nlm.nih.gov/pubmed/31766161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9110279
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