Vaccine Protection against Multidrug-Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection

Klebsiella pneumoniae is a human gut communal organism and notorious opportunistic pathogen. The relative high burden of asymptomatic colonization by K. pneumoniae is often compounded by multidrug resistance—a potential problem for individuals with significant comorbidities or other risk factors for...

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Udgivet i:mBio
Main Authors: Malachowa, Natalia, Kobayashi, Scott D., Porter, Adeline R., Freedman, Brett, Hanley, Patrick W., Lovaglio, Jamie, Saturday, Greg A., Gardner, Donald J., Scott, Dana P., Griffin, Amanda, Cordova, Kathleen, Long, Dan, Rosenke, Rebecca, Sturdevant, Daniel E., Bruno, Daniel, Martens, Craig, Kreiswirth, Barry N., DeLeo, Frank R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918093/
https://ncbi.nlm.nih.gov/pubmed/31848292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02994-19
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