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Quantitative Visualization of Gene Expression in Mucoid and Nonmucoid Pseudomonas aeruginosa Aggregates Reveals Localized Peak Expression of Alginate in the Hypoxic Zone

It is well appreciated that oxygen- and other nutrient-limiting gradients characterize microenvironments within chronic infections that foster bacterial tolerance to treatment and the immune response. However, determining how bacteria respond to these microenvironments has been limited by a lack of...

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發表在:mBio
Main Authors: Jorth, Peter, Spero, Melanie A., Livingston, J., Newman, Dianne K.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918079/
https://ncbi.nlm.nih.gov/pubmed/31848278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02622-19
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