Minocycline fails to improve neurologic and histologic outcome after ventricular fibrillation cardiac arrest in rats

BACKGROUND: Prolonged cardiac arrest (CA) produces extensive neuronal death and microglial proliferation and activation resulting in neuro-cognitive disabilities. Among other potential mechanisms, microglia have been implicated as triggers of neuronal death after hypoxic-ischemic insults. Minocyclin...

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Vydáno v:World J Crit Care Med
Hlavní autoři: Janata, Andreas, Magnet, Ingrid AM, Schreiber, Kristin L, Wilson, Caleb D, Stezoski, Jason P, Janesko-Feldman, Keri, Kochanek, Patrick M, Drabek, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2019
Témata:
Basic Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918046/
https://ncbi.nlm.nih.gov/pubmed/31853446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5492/wjccm.v8.i7.106
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