A computational framework to explore large-scale biosynthetic diversity

Genome mining has become a key technology to exploit natural product diversity. While initially performed on a single-genome basis, the process is now being scaled up to mine entire genera, strain collections and microbiomes. However, no bioinformatic framework is currently available for effectively...

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Publicat a:Nat Chem Biol
Autors principals: Navarro-Muñoz, Jorge C., Selem-Mojica, Nelly, Mullowney, Michael W., Kautsar, Satria A., Tryon, James H., Parkinson, Elizabeth I., De Los Santos, Emmanuel L.C., Yeong, Marley, Cruz-Morales, Pablo, Abubucker, Sahar, Roeters, Arne, Lokhorst, Wouter, Fernandez-Guerra, Antonio, Cappelini, Luciana Teresa Dias, Goering, Anthony W., Thomson, Regan J., Metcalf, William W., Kelleher, Neil L., Barona-Gomez, Francisco, Medema, Marnix H.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917865/
https://ncbi.nlm.nih.gov/pubmed/31768033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0400-9
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