Synergistic Effects of Hyperandrogenemia and Obesogenic Western-style Diet on Transcription and DNA Methylation in Visceral Adipose Tissue of Nonhuman Primates

Polycystic ovary syndrome (PCOS) is a major reproductive disorder that is responsible for 80% of anovulatory infertility and that is associated with hyperandrogenemia, increased risk of obesity, and white adipose tissue (WAT) dysfunction. We have previously demonstrated that the combination of chron...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Carbone, Lucia, Davis, Brett A., Fei, Suzanne S., White, Ashley, Nevonen, Kimberly A., Takahashi, Diana, Vinson, Amanda, True, Cadence, Roberts, Charles T., Varlamov, Oleg
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917716/
https://ncbi.nlm.nih.gov/pubmed/31848372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55291-8
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