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Length-Dependent Activation of Contractility and Ca-Transient Kinetics in Auxotonically Contracting Isolated Rat Ventricular Cardiomyocytes

Length-dependent activation (LDA) of contraction is an important mechanism of proper myocardial function that is often blunted in diseases accompanied by deficient contractility and impaired calcium homeostasis. We evaluated how the extent of LDA is related to the decreased force in healthy rat myoc...

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Veröffentlicht in:Front Physiol
Hauptverfasser: Lookin, Oleg, Protsenko, Yuri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917588/
https://ncbi.nlm.nih.gov/pubmed/31920687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01473
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