Clinical significance of TP53 variants as possible secondary findings in tumor-only next-generation sequencing

In tumor-only next-generation sequencing (NGS), identified variants have the potential to be secondary findings (SFs), but they require verification through additional germline testing. In the present study, 194 patients with advanced cancer who underwent tumor-only NGS between April 2015 and March...

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Foilsithe in:J Hum Genet
Main Authors: Yamamoto, Yoshihiro, Kanai, Masashi, Kou, Tadayuki, Sugiyama, Aiko, Nakamura, Eijiro, Miyake, Hidehiko, Yamada, Takahiro, Nishigaki, Masakazu, Kondo, Tomohiro, Murakami, Hiromi, Torishima, Masako, Matsumoto, Shigemi, Kosugi, Shinji, Muto, Manabu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Singapore 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917569/
https://ncbi.nlm.nih.gov/pubmed/31628423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-019-0681-6
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