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Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor

σ(S) is a master transcription initiation factor that protects bacterial cells from various harmful environmental stresses including antibiotic pressure. Although its mechanism remains unclear, it is known that full activation of σ(S)-mediated transcription requires a σ(S)-specific activator, Crl. I...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Xu, Juncao, Cui, Kaijie, Shen, Liqiang, Shi, Jing, Li, Lingting, You, Linlin, Fang, Chengli, Zhao, Guoping, Feng, Yu, Yang, Bei, Zhang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917491/
https://ncbi.nlm.nih.gov/pubmed/31846423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50928
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