A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage

OBJECTIVE: To test whether the signaling axis CXCL12α‐CXCR4 is activated upon crush/cut of the sciatic nerve and to test the activity of NUCC‐390, a new CXCR4 agonist, in promoting nerve recovery from damage. METHODS: The sciatic nerve was either crushed or cut. Expression and localization of CXCL12...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann Clin Transl Neurol
Egile Nagusiak: Zanetti, Giulia, Negro, Samuele, Megighian, Aram, Mattarei, Andrea, Lista, Florigio, Fillo, Silvia, Rigoni, Michela, Pirazzini, Marco, Montecucco, Cesare
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917312/
https://ncbi.nlm.nih.gov/pubmed/31725979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50926
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