Engineering chitinolytic activity into a cellulose-active lytic polysaccharide monooxygenase provides insights into substrate specificity

Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of recalcitrant polysaccharides such as cellulose and chitin and play an important role in the enzymatic degradation of biomass. Although it is clear that these monocopper enzymes have extended substrate-binding surfaces for int...

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Vydáno v:J Biol Chem
Hlavní autoři: Jensen, Marianne Slang, Klinkenberg, Geir, Bissaro, Bastien, Chylenski, Piotr, Vaaje-Kolstad, Gustav, Kvitvang, Hans Fredrik, Nærdal, Guro Kruge, Sletta, Håvard, Forsberg, Zarah, Eijsink, Vincent G. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916511/
https://ncbi.nlm.nih.gov/pubmed/31656228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010056
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