Engineering chitinolytic activity into a cellulose-active lytic polysaccharide monooxygenase provides insights into substrate specificity

Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of recalcitrant polysaccharides such as cellulose and chitin and play an important role in the enzymatic degradation of biomass. Although it is clear that these monocopper enzymes have extended substrate-binding surfaces for int...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jensen, Marianne Slang, Klinkenberg, Geir, Bissaro, Bastien, Chylenski, Piotr, Vaaje-Kolstad, Gustav, Kvitvang, Hans Fredrik, Nærdal, Guro Kruge, Sletta, Håvard, Forsberg, Zarah, Eijsink, Vincent G. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916511/
https://ncbi.nlm.nih.gov/pubmed/31656228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010056
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