DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models

BACKGROUND: Systemic sclerosis is a multisystem inflammatory and vascular lesion leading to extensive tissue fibrosis. A reversible S-adenosyl-l-homocysteine hydrolase (SAHH) inhibitor, DZ2002, modulates the pathologic processes of various inflammatory diseases and autoimmune diseases. This study is...

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Publicat a:Arthritis Res Ther
Autors principals: Zhang, Zongwang, Wu, Yanwei, Wu, Bing, Qi, Qing, Li, Heng, Lu, Huimin, Fan, Chen, Feng, Chunlan, Zuo, Jianping, Niu, Lili, Tang, Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916442/
https://ncbi.nlm.nih.gov/pubmed/31842999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-2074-9
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