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Modeling appendicular skeletal cartilage development with modified high-density micromass cultures of adult human bone marrow-derived mesenchymal progenitor cells

BACKGROUND: Animal cell-based systems have been critical tools in understanding tissue development and physiology, but they are less successful in more practical tasks, such as predicting human toxicity to pharmacological or environmental factors, in which the congruence between in vitro and clinica...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Pirosa, Alessandro, Clark, Karen L., Tan, Jian, Yu, Shuting, Yang, Yuanheng, Tuan, Rocky S., Alexander, Peter G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916440/
https://ncbi.nlm.nih.gov/pubmed/31842986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1505-5
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