Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial

BACKGROUND: Thiazide diuretics have demonstrated favorable blood pressure lowering efficacy, but the equivalent doses of their more common agents, chlorthalidone and hydrochlorothiazide, are still unclear. Further, concerns exist regarding adverse metabolic effects, which may be attenuated with the...

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Bibliografiske detaljer
Udgivet i:Trials
Main Authors: Martins, Vítor Magnus, Helal, Lucas, Ferrari, Filipe, Bottino, Leonardo Grabinski, Fuchs, Sandra Costa, Fuchs, Flávio Danni
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Study Protocol
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916111/
https://ncbi.nlm.nih.gov/pubmed/31843024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3909-z
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