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FIREVAT: finding reliable variants without artifacts in human cancer samples using etiologically relevant mutational signatures
BACKGROUND: Accurate identification of real somatic variants is a primary part of cancer genome studies and precision oncology. However, artifacts introduced in various steps of sequencing obfuscate confidence in variant calling. Current computational approaches to variant filtering involve intensiv...
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| Veröffentlicht in: | Genome Med |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6916105/ https://ncbi.nlm.nih.gov/pubmed/31847917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0695-x |
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