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The double edge of anti-CD40 siRNA therapy: It increases renal microcapillar density but favours the generation of an inflammatory milieu in the kidneys of ApoE(−/−) mice
BACKGROUND: Chronic kidney disease (CKD) is associated with endothelial dysfunctions thus prompting links between microcirculation (MC), inflammation and major cardiovascular risk factors. PURPOSE OF THE STUDY: We have previously reported that siRNA-silencing of CD40 (siCD40) reduced atherosclerosis...
में बचाया:
| में प्रकाशित: | J Inflamm (Lond) |
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| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6916081/ https://ncbi.nlm.nih.gov/pubmed/31889910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-019-0228-9 |
| टैग : |
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