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HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA

BACKGROUND: The HERV-K (HML-2) viruses are the youngest of the human endogenous retroviruses. They are present as several almost complete proviral copies and numerous fragments in the human genome. Many HERV-K proviruses express a regulatory protein Rec, which binds to an element present in HERV-K m...

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Bibliografski detalji
Izdano u:Retrovirology
Glavni autori: Gray, Laurie R., Jackson, Rachel E., Jackson, Patrick E. H., Bekiranov, Stefan, Rekosh, David, Hammarskjöld, Marie-Louise
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916052/
https://ncbi.nlm.nih.gov/pubmed/31842941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0505-y
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