ROS as a novel indicator to predict anticancer drug efficacy

BACKGROUND: Mitochondria are considered a primary intracellular site of reactive oxygen species (ROS) generation. Generally, cancer cells with mitochondrial genetic abnormalities (copy number change and mutations) have escalated ROS levels compared to normal cells. Since high levels of ROS can trigg...

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Udgivet i:BMC Cancer
Main Authors: Zaidieh, Tarek, Smith, James R., Ball, Karen E., An, Qian
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916036/
https://ncbi.nlm.nih.gov/pubmed/31842863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6438-y
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