The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect

BACKGROUND: Restoration of massive bone defects remains a huge challenge for orthopedic surgeons. Insufficient vascularization and slow bone regeneration limited the application of tissue engineering in bone defect. The effect of electromagnetic field (EMF) on bone defect has been reported for many...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Chen, Jingyuan, Tu, Chang, Tang, Xiangyu, Li, Hao, Yan, Jiyuan, Ma, Yongzhuang, Wu, Hua, Liu, Chaoxu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915868/
https://ncbi.nlm.nih.gov/pubmed/31842985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1464-x
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