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Microsimulation model to predict incremental value of biomarkers added to prognostic models

It is unclear to what extent simulated versions of real data can be used to assess potential value of new biomarkers added to prognostic risk models. Using data on 4522 women and 3969 men who contributed information to the Framingham CVD risk prediction tool, we develop a simulation model that allow...

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Dettagli Bibliografici
Pubblicato in:J Am Med Inform Assoc
Autori principali: Pencina, Karol M, D’Agostino, Ralph B, Vasan, Ramachandran S, Pencina, Michael J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915817/
https://ncbi.nlm.nih.gov/pubmed/30169699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocy108
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