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GJA8 missense mutation disrupts hemichannels and induces cell apoptosis in human lens epithelial cells

Autosomal dominant congenital cataract (ADCC), the most common hereditary disease, is a major cause of eye disease in children. Due to its high genetic and clinical heterogeneity, the identification of ADCC-associated gene mutations is essential for the development of molecular therapies. In this st...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Li, Li, Fan, Da-Bei, Zhao, Ya-Ting, Li, Yun, Yang, Zi-Bing, Zheng, Guang-Ying
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915756/
https://ncbi.nlm.nih.gov/pubmed/31844091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55549-1
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