T4SS-dependent TLR5 activation by Helicobacter pylori infection

Toll-like receptor TLR5 recognizes a conserved domain, termed D1, that is present in flagellins of several pathogenic bacteria but not in Helicobacter pylori. Highly virulent H. pylori strains possess a type IV secretion system (T4SS) for delivery of virulence factors into gastric epithelial cells....

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Vydáno v:Nat Commun
Hlavní autoři: Pachathundikandi, Suneesh Kumar, Tegtmeyer, Nicole, Arnold, Isabelle Catherine, Lind, Judith, Neddermann, Matthias, Falkeis-Veits, Christina, Chattopadhyay, Sujay, Brönstrup, Mark, Tegge, Werner, Hong, Minsun, Sticht, Heinrich, Vieth, Michael, Müller, Anne, Backert, Steffen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915727/
https://ncbi.nlm.nih.gov/pubmed/31844047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13506-6
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