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Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver

Spaceflight has several detrimental effects on the physiology of astronauts, many of which are recapitulated in rodent models. Mouse studies performed on the Space Shuttle showed disruption of lipid metabolism in liver. However, given that these animals were not sacrificed on-orbit and instead retur...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Beheshti, Afshin, Chakravarty, Kaushik, Fogle, Homer, Fazelinia, Hossein, Silveira, Willian A. da, Boyko, Valery, Polo, San-Huei Lai, Saravia-Butler, Amanda M., Hardiman, Gary, Taylor, Deanne, Galazka, Jonathan M., Costes, Sylvain V.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915713/
https://ncbi.nlm.nih.gov/pubmed/31844325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55869-2
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