SIRT1 Protects Against Apoptosis by Promoting Autophagy in the Oxygen Glucose Deprivation/Reperfusion-Induced Injury

Silent information regulator 1 (SIRT1) contributes to cellular regulation. Previous studies have reported SIRT1 to be abnormally expressed in the ischemic penumbra of cerebral ischemia/reperfusion (I/R) injury rat model. We investigated the effect of SIRT1 on oxygen and glucose deprivation/reperfusi...

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Publicado en:Front Neurol
Autores principales: Ren, Qiannan, Hu, Zhiying, Jiang, Yuting, Tan, Xiaoning, Botchway, Benson O. A., Amin, Nashwa, Lin, Gaoping, Geng, Yu, Fang, Marong
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915092/
https://ncbi.nlm.nih.gov/pubmed/31920915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01289
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