miR-98 Modulates Cytokine Production from Human PBMCs in Systemic Lupus Erythematosus by Targeting IL-6 mRNA

OBJECTIVE: There is evidence that interleukin-6 (IL-6) upregulation plays a critical role in immunopathology of systemic lupus erythematosus (SLE). MicroRNA- (miRNA-) 98 was predicted to bind with the 3′-untranslated region (3′-UTR) of IL-6 gene. We hypothesized miR-98 through its regulation of IL-6...

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Udgivet i:J Immunol Res
Main Authors: Yuan, Shiwen, Tang, Chun, Chen, Dongying, Li, Fangfei, Huang, Mingcheng, Ye, Jinghua, He, Zhixiang, Li, Weinian, Chen, Yi, Lin, Xiaojun, Wang, Xiaodong, Cai, Xiaoyan
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914974/
https://ncbi.nlm.nih.gov/pubmed/31886314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9827574
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