NANOG Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence by Upregulating PBX1 and Activating AKT Signaling

Stem cells derived from elderly donors or harvested by repeated subculture exhibit a marked decrease in proliferative capacity and multipotency, which not only compromises their therapeutic potential but also raises safety concerns for regenerative medicine. NANOG—a well-known core transcription fac...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Liu, Feilin, Shi, Jiahong, Zhang, Yingyao, Lian, Aobo, Han, Xing, Zuo, Kuiyang, Liu, Mingsheng, Zheng, Tong, Zou, Fei, Liu, Xiaomei, Jin, Minghua, Mu, Ying, Li, Gang, Su, Guanfang, Liu, Jinyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914946/
https://ncbi.nlm.nih.gov/pubmed/31885790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/4286213
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